Recombinant Galectin 3 antibody (AA 150-200)

Catalog No. ABIN7126641

The Rabbit Monoclonal anti-Galectin 3 antibody has been validated for IHC (f). It is suitable to detect Galectin 3 in samples from Human.

Quick Overview for Recombinant Galectin 3 antibody (AA 150-200) (ABIN7126641)

Target: Galectin 3 (LGALS3)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Galectin 3 antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Product Details anti-Galectin 3 Antibody

Binding Specificity: AA 150-200

Specificity: Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid.Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiationof benign and malignant thyroid neoplasms.Galectin-3 may also be useful in the identification of certain liver disorders.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: A synthetic peptide from the C-terminus of human LGALS3protein (aa 150-200) (exact sequence is proprietary)

Isotype: IgG

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human papillary thyroid carcinoma tissue.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for Galectin 3

Target: Galectin 3 (LGALS3)

Alternative Name: LGALS3

Target Type: Chemical

Background: 35 kDa lectin, Carbohydrate-binding protein 35, CBP35, Gal-3, GAL3, Galactose-specific lectin 3, GALBP, Galectin-3, GALIG, GBP, IgE-binding protein, L-34 galactoside-binding lectin, L31, Laminin-binding protein, Lectin L-29, Lectin, galactose binding, soluble 3, LGALS2, LGALS3, MAC2, Macrophage galactose-specific lectin,Galectin-3 (LGALS3) (Thyroid Cell Marker)
Cellular localisation: Cytoplasm

Molecular Weight: 26kDa

Gene ID: 3958, 531081

UniProt: P17931

Pathways: RTK Signaling